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Problem
How to use Backblaze as S3 Private Cloud storage on Backup Exec 22 or later.
Backblaze is supported as one of S3 Private Cloud Providers on Backup Exec 22. Refer Cloud Storage section - Hardware Compatibility List for Backup Exec 22
Note: The Backblaze S3 Compatible API only supports v4 signatures for authentication and does not support v2 signatures. Refer S3 Compatible API - Backblaze
Solution
Create a cloud instance and a cloud region for Blackblaze using the steps below. Then, create a cloud storage on Backup Exec.
1. Check [Endpoint] after creating a new bucket on Backblaze. (Fig 1).
If the Endpoint is s3.us-west-004.backblazeb2.com, your region is "us-west-004". The endpoint and region are needed to create a cloud instance and a cloud region on Backup Exec Management Command Line Interface.
Fig 1.
2. Ensure to configure [File Versions:] in [Lifecycle Settings] for the Backblaze bucket as [Keep Only Last Version] (Fig 2).
Fig 2.

3. Launch "Backup Exec Management Command Line Interface". Run the commands below to create a cloud instance and a cloud region using the service host and region from 1. above.
New-BECloudInstance -Name "cloudinstance001" -Provider "Compatible-with-s3-v4" -ServiceHost "s3.us-west-004.backblazeb2.com" -HttpPort "80" -HttpsPort "443" -SslMode “Full” –UrlStyle “Path”
New-BECloudRegion -InstanceName "cloudinstance001" -IsDefaultRegion $true -Name "us-west-004" -Identifier "us-west-004" -ServiceHost "s3.us-west-004.backblazeb2.com"
Note: It is recommended that the Instance Name is created with lowercase, like "cloudinstance001".
4. Launch Backup Exec Admin Console and click [Configure Cloud Storage]. (Fig 3)
Fig 3.
4. Select [S3] and press [Next]. (Fig 4)
Fig 4.
5. Select [cloudinstance001 [compatible-with-s3-v4] ] in [Cloud storage] (Fig 5)
"cloudinstance001" is the name of the cloud instance which was created in step #2.
Fig 5.
6. Click [Add/Edit] button at [Logon account] line and add a logon account for Backblaze. (Fig 5)
Go to Blackblaze web console and add a new Application Key giving it a descriptive name. Allow the Application Key rights to listing all buckets and Read and Write access. Oncreated, get the [KeyID] and [ApplicationKey] from the created Application Key. (Fig 6)
NOTE: The image in Fig 6. shows generating a new Master Application Key but
Specify [KeyID] for the [User Name] of the new logon account. Specify [ApplicationKey] for [Password] and [Confirm password].
After creating the Backblaze logon account, make sure it is selected in [Logon account] (Fig 5)
Fig 6.
7. Buckets appear in [which logical storage unit do you want to use?] screen. Select one and press [Next].
8. Press [Finish].
Cloud Storage is created now. Restart the Backup Exec Services and then use the storage for backups and restores.
Note : Only one Blackblaze bucket is applicable to configure in Backup Exec application due to the limitation from private cloud.